CRITICAL CARE PCD FRANCHISE COMPANY IN AZTREONAM
Critical Care PCD Franchise Company In AZTREONAM
Searching for the best one Critical Care PCD Franchise Company in Aztreonam?
Vistica Lifesciences is continually working to ensure that people in need have access to high-quality, affordable medicines.
As a result, health care professionals and patients have put their faith in us. Our main purpose has always been and will continue to be Caring for Life.
We have a different range for the products used in critical care or for critically ill patients, aztreonam is one of our product from the same range which is available for the purpose of critical care PCD franchise company in aztreonam.
Aztreonam is a type of monobactam antibiotics (Monobactams are bacterially generated monocyclic –Beta- lactam antibiotics. Unlike most other beta -lactams, the beta -lactam ring is not bonded to another ring.
Monobactams are only effective against Gram-negative bacteria like Pseudomonas aeruginosa, that are aerobic)
It’s ineffective against Gram positive bacteria and anaerobes. It has been shown to be effective against Citrobacter, Enterobacter, E. coli, Haemophilus, Klebsiella, Proteus, and Serratia species, among others. The chemical formula for Aztreonam is C13H17N5O8S2.
Properties
Beta lactam antibiotic
clinically useful potency against gram negative bacteria such as Enterobacteriaceae, H.influenzae, Pseudomonas spp. & N. gonorrhoeae
Effective, well tolerated and safe therapy for uncomplicated gonococcal urethritis & also for endocervical & rectal infection
Effective for severe UTIs caused by Enterobacteriaceae
Treats gram negative bacillary meningitis in patients with and without inflamed meninges
Therapeutic response & Indications
VIstica Life – Critical Care PCD Franchise Company in Aztreonam is a monobactam antibiotics which is majorly prescribed to treat the infections occurred due to gram negative bacteria.
Aztreonam may be prescribed in following indications
Lower respiratory tract infection
Skin & skin structure infection
Intra abdominal infection
Urinary tract infection & endometritis
Gynecologic infections
Septicemia & sepsis
Pneumonia
Bone infections
Side Effects
Pain at the injection site, vomiting, and rash are all common side effects when administered by injection. When breathed, common adverse effects include wheezing, coughing, and vomiting. Clostridium difficile infection and allergic responses, including anaphylaxis, are serious adverse effects.
Aztreonam allergy is uncommon among those allergic to other -lactams. It appears to be safe to use during pregnancy so its is not contraindicated in pregnancy.
In the United States, Aztreonam was licenced for the purpose of medicinal use in 1986. In the year 2019, it was taken off the WHO’s List of Essential Medicines . It can be purchased as a generic drug. It is a synthetic form of a chemical produced by the Chromobacterium violaceum bacteria.
We at Vistica Lifesciences presenting as Critical Care PCD Franchise Company in Aztreonam. We have Aztreonam in different strengths one is Aztreonam 500mg & another one is Aztreonam 1 gm. Our brand name is Sazonam.
| Sazonam- 500 MG | Aztreonam 500mg inj | 1’s |
| Sazonam- 1 GM | Aztreonam 1gm inj | 1’s |
Mechanism of action
Aztreonam works on the same principle as that of penicillin. By preventing peptidoglycan crosslinking, it prevents the bacterial cell wall from being synthesised. It shows a strong preference for penicillin-binding protein-3 and a weak preference for penicillin-binding protein-1a.
Aztreonam binds poorly to Gram-positive and anaerobic bacteria’s penicillin-binding proteins and most of the time is not effective against them. Aztreonam is bactericidal in nature.
Pharmacokinetics
Absorption- After following oral dosing, it gets absorbed less than 1 percent from the gastro intestinal tract and following intramuscular administration, it is completely absorbed.
The volume of distribution appears to be 12.6 L
Protein Binding- Serum protein binding is 56 percent on average and dose-independent. Renal dysfunction affects 36 to 43 percent of people.
Metabolism- By hydrolysis of the beta-lactam link, approximately 6 to 16 percent of the molecule is converted to the inactive metabolites, as a result an open-ring compound observed.
Route of elimination- Aztreonam is eliminated in the urine through active tubular secretion and glomerular filtration nearly equally in healthy people. A single parenteral dose was almost completely excreted in the urine 12 hours after injection.
Half Life- Aztreonam’s serum half life was 1.7 hours (1.5 to 2.0) in participants, with normal renal function regardless of dosage. The mean serum half life of aztreonam rose in older patients and those with impaired renal function (4.7 to 6 hours and 2.1 hours, respectively).
Clearance- The clearance has been found 91ml per minute for a healthy person.
So, if you’re seeking for the greatest critical care PCD franchise company in Aztreonam, you can contact Vistica Lifesciences immediately. Vistica Life Sciences is a leading brand in critical care pcd franchise company pan India. We serve quality products manufacture in GMP certified manufacturing plants under highly skilled professionals.
